CanBioSe project meeting and workshop at International Conference on Nanomaterials for biosensors and biomedical applications, Jurmala, Latvia

 International Conference on Nanomaterials for biosensors and biomedical applications, Jurmala, Latvia

MRC representatives, Oleksiy Gogotsi and Veronika Zahorodna attended CanBioSe project meeting held during International Conference on Nanomaterials for biosensors and biomedical applications, Jurmala, Latvia, on July 2019.

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MRC director Oleksiy Gogotsi made an oral presentaion on MXenes for biosensors and biomedical applications.

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MXenes for biosensors and biomedical applications

Oleksiy Gogotsia, b, Veronika Zahorodnaa, b, Vitalii Balitskyia, , Mykola Seredych c, Qi Zhao c, Yury Gogotsi c

a Materials Research Centre, Kyiv 03680, Ukraine

b National Metallurgical Academy of Ukraine, Dnipro 49600, Ukraine

c Department of Materials Science & Engineering and A.J. Drexel Nanomaterials Institute, Drexel University, Philadelphia, Pennsylvania 19104, United States

2-Dimensional transition metal carbides and nitrides (MXenes) - discovered at Drexel University [1] hold tremendous potential as new materials for biomedial applications. MXenes are produced by selective etching of the A elements (mostly Al) from their ternary layered 3D Mn+1AXn, phase counterparts, where M is an early transition metal, A is an A-group element, X is C and/or N, and n = 1 to 3 [2]. In contrast to raw Mn+1AXn phases, the MXene sheets are oxygenated (═O, −OH) and fluorinated (–F) for preferential sorption of target biomolecules. Beyond the characteristics shared by all 2D materials, MXenes stand out in several ways. They are: i) conductive, with high density of states at the Fermi level and metal-like carrier densities; ii) hydrophilic, and thus processable in eco-friendly and sustainable ways; iii) extraordinarily and readily tailorable at multiple levels. MXenes have already shown promising performance in many applications includingdrug delivery and photothermal therapy [3], antibacterial activity [4], electrodes and sensors for medicine [5, 6],selective sorption of small molecules such as urea removal in wearable dialysis systems [7]. Moreover, cytotoxic tests show no significant effect on cell viability during 24 h incubation with 3T3 fibroblast cells by the titanium carbide MXenes [7]. This kind of MXenes sorbents offer open accessible surfaces fully available for proteins and can also be used in treatment of a broad range of conditions ranging from radiation disease and drug overdose to Ebola, Crohn’s disease, Ankylosing Spondylitis and other conditions related to cytokines or toxin in blood.

 References

[1] M. Naguib, et al. Two-dimensional nanocrystals produced by exfoliation of Ti3AlC2. Advanced Materials 2011, 23, 4248.

[2] B. Anasori, et al. 2D metal carbides and nitrides (MXenes) for energy storage. Nature Review Materials 2017, 16098, 1.

[3] C. Dai, et al. Two-dimensional tantalum carbide (MXenes) composite nanosheets for multiple imaging-guided photothermal tumor ablation. ACS Nano 2017, 11, 12696.

[4] K.Rasool, et al. Antibacterial activity of Ti3C2Tx MXene. ACS Nano 2016, 10, 3674.

[5] N. Driscoll, et al. Two-dimensional Ti3C2 MXene for high-resolution neural interfaces

ACS Nano 2018, 12, 1041.

Abstract book of the Conference

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About CanBioSe Project 

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News from MRC.ORG.UA

Twenty Third Annual Conference - YUCOMAT 2022 Twelfth World Round Table Conference on Sintering - XII WRTCS 2022 Herceg Novi, August 29 – September 2, 2022

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Our collaborators and partners  presented our joint research at the Yucomat conference - at Symposium on Biomaterials and two collaborative posters at Conference Poster Session.

 
MRC team visited 2nd international MXene conference "MXenes: Addressing Global Challenges with Innovation"at Drexel University, USA on Aug. 1-3, 2022

second MXene COnference 2022, Drexel University, USA

MRC team members Dr. Oleksiy Gogotsi, Veronika Zahorodna, Dr. Iryna Roslyk visited MXene Confrence 2022.  This 2nd international MXene conference at Drexel University, August 1-3, 2022, put major MXene discoveries, including their record-breaking electrical conductivity, electromagnetic interference shielding capability, electrochemical capacitance, light-to-heat conversion, and other properties, into perspective.

 
Launching HORIZON-MSCA-2021-SE-01 MX-MAP Project: Towards MXenes biomedical applications by high-dimensional immune MAPping

MX-MAP project Meeting during the MXene international conference held in Drexel University on Aug. 3,  2022, and discussing the roadmap for launching MX-MAP research project on MXenes for medical applications.

 
H2020-MSCA-RISE NANO2DAY research project, last updates

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Researchers from University of Latvia and Materials Research Center, Ukraine are visiting Drexel University due to Horizon-2020-MSCA-RISE NANO2DAY research project.

 
MXene-Assisted Ablation of Cells with a Pulsed Near-Infrared Laser

Development of tailored MXene PTT treatment targeting tumor cells. We demonstrate both low toxicity and good biocompatibility of this MXene in vitro, as well as a favorable safety profile based on the experiments in vivo.Presenting our recent collaborative research paper on  MXene use for PPT anticancer therapy, the biocompatibility of MXenes in vitro and in vivo studies:

Sergiy Kyrylenko, Oleksiy Gogotsi, Ivan Baginskiy, Vitalii Balitskyi, Veronika Zahorodna, Yevheniia Husak, Ilya Yanko, Mykolay Pernakov, Anton Roshchupkin, Mykola Lyndin, Bernhard B. Singer, Volodymyr Buranych, Alexander Pogrebnjak, Oksana Sulaieva, Oleksandr Solodovnyk, Yury Gogotsi, Maksym Pogorielov, MXene-Assisted Ablation of Cells with a Pulsed Near-Infrared Laser. ACS Appl. Mater. Interfaces 2022, 14, 25, 28683–28696, https://doi.org/10.1021/acsami.2c08678

 
MXenes—A New Class of Two-Dimensional Materials: Structure, Properties and Potential Applications

Presenting our collaborative paper on recen advances in MXene research and their potential applications:

Pogorielov M, Smyrnova K, Kyrylenko S, Gogotsi O, Zahorodna V, Pogrebnjak A. MXenes—A New Class of Two-Dimensional Materials: Structure, Properties and Potential Applications. Nanomaterials. 2021; 11(12):3412. https://doi.org/10.3390/nano11123412

 
MXene nanoflakes decorating ZnO tetrapods for enhanced performance of skin-attachable stretchable enzymatic electrochemical glucose sensor

Presenting our joint research paper supported by CANBIOSE research project: and published in Biosensors and Bioelectronics: MXene nanoflakes decorating ZnO tetrapods for enhanced performance of skin-attachable stretchable enzymatic electrochemical glucose sensor

 
If you want to help and support the purchase of aid consignments, shipping cost to Ukraine and delivery within Ukraine to the places in nee, please donate

Our volunteersBig thanks to all our friends, partners, volunteers for help and their tireless work! We continue to help our defenders and deliver military equipment, humanitarian aid, tactical medicine and special medical supplies to units of Ukrainian Army, territorial defense and hospitals on the front line!

 
Delivering help to Ukraine from the USA, Europe, and the rest of the world!

3.jpg - 197.81 KbOur organization in Kyiv, Materials Research Center, is well aware of the needs in Ukraine now. Together with our partners, fellow Ukrainian scientists, we have organized a warehouse in Lviv, where we collect cargos and distribute them throughout Ukraine, with detailed reports confirming the delivery to the final destination, including photos of the transfer. We have transportation that can pick cargo in Poland and deliver it through a green corridor for humanitarian cargos at the Polish-Ukrainian border. 
We are ready to respond promptly, as required by the situation in Ukraine. If there are individuals, foundations or volunteer organizations willing to send help to Ukraine from Europe or the United States, we are ready to accept it in our warehouses, make collection or individual parties according to your request and pass them on to those in need. All humanitarian aid, first aid, and protective gear will be delivered to the final destination.
Please contact Dr. Oleksiy Gogotsi, MRC Director: Tel / Viber / WhatsApp / Telegram / Signal: + 380 63 233 2443, Cell phone in the USA: +1 808 203 8092, e-mail: helpukraine@mrc.org.ua
Being currently on a business trip in Philadelphia, the United States, we can meet with you in person, if needed.

 
MRC Ukraine Foundation. Providing of military first aid medicine for the Special Operations Forces of the Armed Forces of Ukraine

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MRC Ukraine Foundation. Providing of military first aid medicine for the Special Operations Forces of the Armed Forces of Ukraine via volunteers. Specialized military first aid medical supplies were provided by the Special Forces Foundation, Green Berets Humanitarian Fund, USA

 
Delivering military first aid medicine from the Special Forces Foundation Green Beret Humanitarian Fund (GBHF) from the USA to territorial defences, army unit and 2 hospitals

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Delivering military first aid medicine from the Special Forces Foundation Green Beret Humanitarian Fund (GBHF) from the USA via the Kernel Volunteer Group for the Territorial Defense of Kyiv, Poltava, Vinnytsia, Voznesensk, as well as some military unit in Kyiv and Ternopil. Also part of medical supplies is transferred to hospitals in Krasnopillia in Sumy region and Voznesensk in Mykolaiv region

 

 
MRC Ukraine Foundation. Transfer of military first aid medicine at our hub in Lviv

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MRC Ukraine Foundation. Transfer of military first aid medicine at our hub in Lviv from the American Green Beret Humanitarian Fund for some military units.

 
BSU and LU parthers secondment visits to MRC an seminar discussion of ongoing research works under the NANO2DAY project at Materials Research Center, February 2022

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During the secondment visits of project partners from BSU and LU to MRC research works were performed and a seminar discussion of ongoing research works and obtained results was held under the NANO2DAY project.

 
Registration is now open for the upcoming MXene Certificate Course, February 7-11, 2022 from Professor Yury Gogotsi and his team, Drexel University, USA

altRegistration is now open for the upcoming MXene Certificate Course, February 7-11, 2022! This virtual certificate course will teach best practices for the synthesis (2 days), characterization (2 days), and electrochemical measurements of MXenes with a new lecture in the biomedical applications of MXenes (you may choose electrochemical measurements OR biomedical applications - 1 day).

 
Visiting resracher S. Stankevich performed secondment to MRC due to NANO2DAY project

altStanislav Stankevich, research assistant from Latvias University, Riga, Latvia, performed secondment visit to Materials Research Center, Kyiv, Ukraine, due to the MSCA RISE research project NANO2DAY working on project tasks related to MXene based composites. Dates of performed secondment visit November 17-December 16, 2021.